American depositary receipts of European stocks were trading 0.78% lower at 126.80 on the Bank of New York Mellon Europe ADR Index on Thursday. In continental Europe, the gainers were led by biotech company Forward Pharma (FWP) and hotel booking site Trivago (TRVG), which rose 2.4% and 2% respectively. They were followed by kidney dialysis company Fresenius Medical Care (FMS) and pharmaceutical firm Grifols (GRFS), which were up 1.9% and 1%.

The decliners in continental Europe were led by semiconductor company Sequans Communications (SQNS) and Deutsche Bank (DB), which fell 9.1% and 4.9% respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and semiconductor company STMicroelectronics (STM), which dropped 3.5% and 3.3%. In the UK and Ireland, the gainers were led by medical equipment maker Smith & Nephew (SNN) and biopharmaceutical company Akari Therapeutics (AKTX), which were up 4.6% and 2.1% respectively. They were followed by alcoholic beverage company Diageo (DEO) and gene therapy company Nightstar (NITE), which rose 2.1% and 1.3%.

The decliners in the UK and Ireland were led by pharmaceutical company Avadel (AVDL), which tumbled 23.1%, followed by communications group WPP (WPP), which dropped 4%. Biopharmaceutical companies Adaptimmune Therapeutics (ADAP) and GW Pharmaceuticals (GWPH) were off 3.3% and 2.2%.

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